International Federation of Clinical Chemistry standardization project for measurements of apolipoproteins A-I and B.

International Federation of Clinical Chemistry standardization project for measurements of apolipoproteins A-I and B. IV. Comparability of apolipoprotein B values by use of International Reference Material.

We performed temporal and thermal stability studies on SP3-07, a liquid-stabilized reference material for apolipoprotein (apo) B, selected during the previous phase of the International Federation of Clinical Chemistry project on standardization of apolipoprotein measurements. Results indicate that SP3-07 stored at -70 degrees C has the long-term stability required for a reference material. We ...

Reference Materials for the Standardization of the Apolipoproteins A-I and B, and Lipoprotein(a)

Measurement of the apolipoproteins A-I and B, and lipoprotein(a) enable identification of individuals at increased risk of cardiovascular disease. However, the lack of standardized methods to measure these risk markers has resulted for many years in the noncomparability of values and often a conflicting interpretation of clinical studies. Due to the collaborative efforts of the International Fe...

International Federation of Clinical Chemistry (IFCC): Scientific Division, Committee on Apolipoproteins; Working Group of Antibody Reagents: Selection and Characterization of Monoclonal Antibodies for Measuring Plasma Levels of Apolipoproteins A-I and B

International Federation of Clinical Chemistry standardization project for the measurement of lipoprotein(a). Phase I. Evaluation of the analytical performance of lipoprotein(a) assay systems and commercial calibrators.

A secondary reference material for lipoprotein(a) is required to standardize the measurement of lipoprotein(a) in clinical laboratories worldwide. Towards this aim, the International Federation of Clinical Chemistry Working Group for the Standardization of Lipoprotein(a) Assays has initiated a standardization project involving a total of 33 diagnostic company and clinical chemistry laboratories...

Effects of lyophilization of serum on the measurement of apolipoproteins A-I and B.

A common accuracy-based standardization program is indispensable for establishing reference intervals for the clinical use of apolipoproteins. The development and distribution of reference materials and quality-control materials that do not exhibit matrix effects between methods is essential to the standardization process. We examined the suitability of lyophilized material as a common referenc...